Pharmacokinetics for All

We want to highlight how differences in diet, human physiology and biochemistry between individuals can affect the absorption, distribution, metabolism and excretion of drugs and we’re challenging existing thinking about how ethnicity can play a role.

Scoping Review Published

We have recently published our scoping review!

Inter-ethnic differences in pharmacokinetics—is there more that unites than divides?

Olusola Olafuyi, Nikita Parekh, Jacob Wright, Jennifer Koenig
First published: 02 November 2021 https://doi.org/10.1002/prp2.890
Funding information:
This research was funded by the British Pharmacological Society (BPS).

Do you teach pharmacokinetics? Or know someone who does?

We have designed some teaching materials that address inter-individual variation in pharmacokinetics and encourages students to think about the meaning of ethnicity in this context.

If you would like to trial these materials in your institution, please get in touch by email to Jennifer.koenig@nottingham.ac.uk and olusola.olafuyi@nottingham.ac.uk

Everyone is different. The way the human body handles medicines varies due to lots of factors. Current teaching covers differences in the young and old and during pregnancy and although we know there can be differences between ethnic groups, we’re thinking about what to teach about this and how.

In the first phase of this project we collected evidence about how medicines can be absorbed into the body, distributed within the body and metabolised and excreted and find out how this varies between people. We also investigated the education research literature to find out how ethnicity is currently taught.

In the second phase of the project we have turned the evidence we’ve collected into high quality teaching materials and in 2022 we will trial and evaluate these with our students before sharing with other universities.

With thanks to the British Pharmacological Society for a Teaching Grant Award to support the freelance project officer role.

Dr Shola Olafuyi

Assistant Professor in Pharmacology,

School of Life Sciences, University of Nottingham.

Dr Jenny Koenig

Assistant Professor in Pharmacology, Therapeutics and Toxicology,

Division of Medical Sciences & Graduate Entry Medicine, University of Nottingham.